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KMID : 0360220170580030321
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Journal of the Korean Ophthalmological Society
2017 Volume.58 No. 3 p.321 ~ p.326
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The Effectiveness of Visual Field C10-2 in the Early Detection of Glaucoma with Parafoveal Scotoma
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Hwang Bo-Een
Park Hae-Young
Park Chan-Kee
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Abstract
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Purpose: To identify the correspondence between the central sensitivity of several visual field (VF) tests and ganglion cell inner plexiform layer (GC-IPL) thickness in early glaucoma patients with parafoveal scotoma.
Methods: Fifty-seven eyes from 57 patients with glaucomatous optic neuropathy and parafoveal scotoma were analyzed using the standard automated perimetry (SAP) C10-2 test, the SAP C24-2 test, and the frequency doubling technology perimetry (FDT) C24-2 test. The correlation between the VF central sensitivity and the GC-IPL thickness from macular scans via optical coherence tomography was analyzed.
Results: The central sensitivity was 27.51 ± 5.43 dB, 27.39 ± 5.05 dB, and 22.09 ± 5.08 dB for SAP C24-2, SAP C10-2, and FDT C24-2, respectively. Mean GC-IPL thickness was 70.2 ± 8.5 μm. Using regression analysis, the value of log R2 between the logarithmic central sensitivity and GC-IPL thickness was 0.498, and the linear R2 between the antilogarithmic central sensitivity and GC-IPL thickness in SAP C10-2 was 0.486, and both were statistically significant (p < 0.05). This relationship was stronger in early glaucoma patients compared to late glaucoma patients using SAP C10-2.
Conclusions: The structure-function relationship between GC-IPL thickness and central sensitivity was better with SAP C10-2, especially in early glaucoma patients, compared to other VF modalities.
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KEYWORD
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C10-2, Early glaucoma, Optical coherence tomography, Parafoveal scotoma, Structure-function analysis
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